| Title | Publisher | Year | Language | Documents |
|---|---|---|---|---|
| Sacrifice to the Spider Queen | Avimar | 1985 | English | |
| Safe As Houses | Teachers Pet Software | 1989 | English | |
| Schat van de Inca's, De | Addison-Wesley Publishers |
1985 | Dutch | Solution |
| Search For Sanity | John Carpenter | 1987 | English | Solution |
| Secret Diary of Adrian Mole Aged 13 ¾, The | Level 9 Computing |
1985 | English | Solution, Hints |
| Sinferidad | Benjamín Escalonilla Godayol | 2010 | Spanish | |
| Sons of the Cherry, The | Alex Livingston | 2010 | English | |
| Spanish Gold | Chalksoft |
1983 | English | Solution |
| Sparkstone, The: Episode 1 of the Tales of Florb | Roby Sherman | 2019 | English | |
| Spéléologie en Aveugle! | Mickael Pernot | 2020 | French | Solution |
| Stellaris 3 | SPECTRAVENTURA | 2011 | Spanish | |
| Strange Submarine | Chaotic Soft, MilousSoft | 1990 | Czech | |
| Survival Messenger | Vintage Computer Carinthia | 2020 | English | Solution |